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Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels
Many ion channels show low basal activity which is increased hundreds fold by the relevant gating factor. A classical example is the activation G protein activated K(+) channels (GIRK) by Gβγ subunit dimer. The extent of activation (relative to basal current), R(a), is an important physiological par...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832599/ https://ncbi.nlm.nih.gov/pubmed/18622586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9117-z |
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