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c-Jun NH(2)-Terminal Kinase Is Required for Lineage-Specific Differentiation but Not Stem Cell Self-Renewal
The c-Jun NH(2)-terminal kinase (JNK) is implicated in proliferation. Mice with a deficiency of either the Jnk1 or the Jnk2 genes are viable, but a compound deficiency of both Jnk1 and Jnk2 causes early embryonic lethality. Studies using conditional gene ablation and chemical genetic approaches demo...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832508/ https://ncbi.nlm.nih.gov/pubmed/20065035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00795-09 |
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