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d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila

dTOR (target of rapamycin) and dFoxo respond to changes in the nutritional environment to induce a broad range of responses in multiple tissue types. Both dTOR and dFoxo have been demonstrated to control the rate of age-related decline in cardiac function. Here, we show that the Eif4e-binding protei...

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Detalhes bibliográficos
Main Authors: Wessells, Robert, Fitzgerald, Erin, Piazza, Nicole, Ocorr, Karen, Morley, Samantha, Davies, Claire, Lim, Hui-Ying, Mitchell, Lisa, Hayes, Michael, Oldham, Sean, Bodmer, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832479/
https://ncbi.nlm.nih.gov/pubmed/19594484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00504.x
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