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Regulation of cellular growth by the Drosophila target of rapamycin dTOR

The TOR protein kinases (TOR1 and TOR2 in yeast; mTOR/FRAP/RAFT1 in mammals) promote cellular proliferation in response to nutrients and growth factors, but their role in development is poorly understood. Here, we show that the Drosophila TOR homolog dTOR is required cell autonomously for normal gro...

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Autors principals: Zhang, Hongbing, Stallock, James P., Ng, Joyce C., Reinhard, Christoph, Neufeld, Thomas P.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317034/
https://ncbi.nlm.nih.gov/pubmed/11069888
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