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WWOX gene and gene product: tumor suppression through specific protein interactions

The WWOX gene, an archetypal fragile gene, encompasses a chromosomal fragile site at 16q23.2, and encodes the approximately 46-kDa Wwox protein, with WW domains that interact with a growing list of interesting proteins. If the function of a protein is defined by the company it keeps, then Wwox is in...

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Autors principals: Salah, Zaidoun, Aqeilan, Rami, Huebner, Kay
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832309/
https://ncbi.nlm.nih.gov/pubmed/20146584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.152
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