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Entering the lysosome through a transient gate by chaperone-mediated autophagy

A subset of cytosolic proteins can be selectively degraded in lysosomes through chaperone-mediated autophagy. The lysosomal-membrane protein type 2A (LAMP-2A) acts as the receptor for the substrates of chaperone-mediated autophagy (CMA), which should undergo unfolding before crossing the lysosomal m...

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Bibliografski detalji
Glavni autori: Bandyopadhyay, Urmi, Cuervo, Ana Maria
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832301/
https://ncbi.nlm.nih.gov/pubmed/18927485
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