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The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

Chaperone-mediated autophagy (CMA) is a selective type of autophagy by which specific cytosolic proteins are sent to lysosomes for degradation. Substrate proteins bind to the lysosomal membrane through the lysosome-associated membrane protein type 2A (LAMP-2A), one of the three splice variants of th...

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Autors principals: Bandyopadhyay, Urmi, Kaushik, Susmita, Varticovski, Lyuba, Cuervo, Ana Maria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546938/
https://ncbi.nlm.nih.gov/pubmed/18644871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02070-07
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