Improving Outcomes of Neuroprotection by Minocycline: Guides from Cell Culture and Intracerebral Hemorrhage in Mice

Minocycline ameliorates deficits in models of acute and chronic neurological diseases, but many publications do not replicate these results. We tested the hypothesis that a key factor in achieving neurological benefits is the exposure of neural cells to local high concentrations of minocycline. This...

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Autores principales: Xue, Mengzhou, Mikliaeva, Elena I., Casha, Steve, Zygun, David, Demchuk, Andrew, Yong, V. Wee
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2010
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832142/
https://ncbi.nlm.nih.gov/pubmed/20110416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090361
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