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Improving Outcomes of Neuroprotection by Minocycline: Guides from Cell Culture and Intracerebral Hemorrhage in Mice

Minocycline ameliorates deficits in models of acute and chronic neurological diseases, but many publications do not replicate these results. We tested the hypothesis that a key factor in achieving neurological benefits is the exposure of neural cells to local high concentrations of minocycline. This...

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Detalhes bibliográficos
Main Authors: Xue, Mengzhou, Mikliaeva, Elena I., Casha, Steve, Zygun, David, Demchuk, Andrew, Yong, V. Wee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832142/
https://ncbi.nlm.nih.gov/pubmed/20110416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090361
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