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Improving Outcomes of Neuroprotection by Minocycline: Guides from Cell Culture and Intracerebral Hemorrhage in Mice

Minocycline ameliorates deficits in models of acute and chronic neurological diseases, but many publications do not replicate these results. We tested the hypothesis that a key factor in achieving neurological benefits is the exposure of neural cells to local high concentrations of minocycline. This...

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Autori principali: Xue, Mengzhou, Mikliaeva, Elena I., Casha, Steve, Zygun, David, Demchuk, Andrew, Yong, V. Wee
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832142/
https://ncbi.nlm.nih.gov/pubmed/20110416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090361
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