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Bone Morphogenetic Protein-7 Inhibits Proximal Tubular Epithelial Cell Smad3 Signaling via Increased SnoN Expression
Bone morphogenetic protein-7 (BMP-7) improves outcome in animal models of fibrotic renal disease by opposing transforming growth factor β1 (TGF-β)-dependent fibrosis. However, the underlying mechanisms remain obscure. Here, we studied the effect of BMP-7 on response to TGF-β in the proximal tubular...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832137/ https://ncbi.nlm.nih.gov/pubmed/20093492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090459 |
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