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Arsenic Exposure Transforms Human Epithelial Stem/Progenitor Cells into a Cancer Stem-like Phenotype

BACKGROUND: Inorganic arsenic is a ubiquitous environmental carcinogen affecting millions of people worldwide. Evolving theory predicts that normal stem cells (NSCs) are transformed into cancer stem cells (CSCs) that then drive oncogenesis. In humans, arsenic is carcinogenic in the urogenital system...

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Bibliografiset tiedot
Päätekijät: Tokar, Erik J., Diwan, Bhalchandra A., Waalkes, Michael P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Institute of Environmental Health Sciences 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831952/
https://ncbi.nlm.nih.gov/pubmed/20056578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901059
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