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Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

BACKGROUND: Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2)-mediated survival signaling is critical to endothelial cell survival, maintenance of the vasculature and alveolar structure and regeneration of lung tissue. Reduced VEGF and VEGFR2 expression in emphysematous lungs ha...

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Main Authors: Marwick, John A, Edirisinghe, Indika, Arunachalam, Gnanapragasam, Stevenson, Christopher S, MacNee, William, Kirkham, Paul A, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831890/
https://ncbi.nlm.nih.gov/pubmed/20205917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-7-11
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