Role of Adrenal Cortical Function in Toxicity of Polyriboinosinic·Polyribocytidylic Acid and Its Component Homopolymers

Adrenalectomized rats are 1000 times more sensitive to lethal effects of the double-stranded complex polyriboinosinic·polyribocytidylic acid than intact rats. They are protected from such lethal effects by corticosterone. The complex can rapidly induce diffuse, severe necrosis of villous epithelium...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Zedeck, Morris S., Marquardt, Hans, Sternberg, Stephen S., Fleisher, Martin, Hamilton, L. D.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1970
Предметы:	Biological Sciences: Microbiology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5272311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.1.180
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