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Role of Adrenal Cortical Function in Toxicity of Polyriboinosinic·Polyribocytidylic Acid and Its Component Homopolymers

Adrenalectomized rats are 1000 times more sensitive to lethal effects of the double-stranded complex polyriboinosinic·polyribocytidylic acid than intact rats. They are protected from such lethal effects by corticosterone. The complex can rapidly induce diffuse, severe necrosis of villous epithelium...

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Autori principali: Zedeck, Morris S., Marquardt, Hans, Sternberg, Stephen S., Fleisher, Martin, Hamilton, L. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1970
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC283185/
https://ncbi.nlm.nih.gov/pubmed/5272311
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