Role of Adrenal Cortical Function in Toxicity of Polyriboinosinic·Polyribocytidylic Acid and Its Component Homopolymers
Adrenalectomized rats are 1000 times more sensitive to lethal effects of the double-stranded complex polyriboinosinic·polyribocytidylic acid than intact rats. They are protected from such lethal effects by corticosterone. The complex can rapidly induce diffuse, severe necrosis of villous epithelium...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1970
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5272311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.1.180 |
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