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Characterization of residual structure in the thermally denatured state of barnase by simulation and experiment: Description of the folding pathway

Residual structure in the denatured state of a protein may contain clues about the early events in folding. We have simulated by molecular dynamics the denatured state of barnase, which has been studied by NMR spectroscopy. An ensemble of 10(4) structures was generated after 2 ns of unfolding and fo...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Bond, Chris J., Wong, Kam-Bo, Clarke, Jane, Fersht, Alan R., Daggett, Valerie
التنسيق: Artigo
اللغة:Inglês
منشور في: The National Academy of Sciences of the USA 1997
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC28318/
https://ncbi.nlm.nih.gov/pubmed/9391038
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