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HCMV IL-10 Suppresses Cytokine Expression in Monocytes Through Inhibition of Nuclear Factor-κB

Modulation of host immune responses is a common strategy for promoting virus persistence and avoiding clearance. Human cytomegalovirus (HCMV) is known to encode numerous immunomodulatory genes, including a homolog of the cytokine human interleukin-10 (hIL-10). While having limited sequence homology...

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Detalhes bibliográficos
Main Authors: Nachtwey, James, Spencer, Juliet V.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831744/
https://ncbi.nlm.nih.gov/pubmed/19115937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2008.0048
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