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The Cytomegalovirus Homolog of Interleukin-10 Requires Phosphatidylinositol 3-Kinase Activity for Inhibition of Cytokine Synthesis in Monocytes
Human cytomegalovirus (CMV) has evolved numerous strategies for evading host immune defenses, including piracy of cellular cytokines. A viral homolog of interleukin-10, designated cmvIL-10, binds to the cellular IL-10 receptor and effects potent immune suppression. The signaling pathways employed by...
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797587/ https://ncbi.nlm.nih.gov/pubmed/17121792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01655-06 |
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