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The Cytomegalovirus Homolog of Interleukin-10 Requires Phosphatidylinositol 3-Kinase Activity for Inhibition of Cytokine Synthesis in Monocytes
Human cytomegalovirus (CMV) has evolved numerous strategies for evading host immune defenses, including piracy of cellular cytokines. A viral homolog of interleukin-10, designated cmvIL-10, binds to the cellular IL-10 receptor and effects potent immune suppression. The signaling pathways employed by...
Uloženo v:
| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2007
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797587/ https://ncbi.nlm.nih.gov/pubmed/17121792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01655-06 |
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