Polynucleotide Ligase-Catalyzed Joining of Deoxyribo-oligonucleotides on Ribopolynucleotide Templates and of Ribo-oligonucleotides on Deoxyribopolynucleotide Templates

T4 polynucleotide ligase efficiently catalyzes the head-to-tail joining of the ribo-oligoadenylates, r-(pA)(8) and r-(pA)(10), in the presence of high molecular weight deoxypolythymidylate. The enzyme also catalyzes the joining of deoxy-oligothymidylates, e.g., d-(pT)(10), in the presence of ribopol...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kleppe, K., van de Sande, J. H., Khorana, H. G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1970
Soggetti:	Biological Sciences: Biochemistry
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5272330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.1.68
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