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Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells

A prothrombotic state in obesity may be partially responsible for the higher incidence of atherosclerotic complications. However the factors responsible for this prothrombotic state, linked with high levels of plasminogen activator inhibitor-1 (PAI-1), are not fully known. Leptin is elevated in obes...

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Hlavní autoři: Singh, Prachi, Peterson, Timothy E., Barber, Kara R., Kuniyoshi, Fatima Sert, Jensen, Andrus, Hoffmann, Michal, Shamsuzzaman, Abu S.M., Somers, Virend K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831408/
https://ncbi.nlm.nih.gov/pubmed/20051227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.12.158
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