Leptin signaling in adipose tissue: Role in lipid accumulation and weight gain

RATIONALE: The link between obesity, hyperleptinemia, and development of cardiovascular disease are not completely understood. Increases in leptin have been shown to impair leptin signaling via caveolin-1 dependent mechanisms. However the role of hyperleptinemia versus impaired leptin signaling in a...

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Autori principali: Singh, Prachi, Peterson, Timothy E., Sert-Kuniyoshi, Fatima H., Glenn, Jason A, Davison, Diane E, Romero-Corral, Abel, Pusalavidyasagar, Snigdha, Jensen, Michael D, Somers, Virend K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482005/
https://ncbi.nlm.nih.gov/pubmed/22730441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.273656
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