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Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase
CpG dinucleotides are mutational hotspots associated with cancer and genetic diseases. Thymine DNA glycosylase (TDG) plays an integral role in CpG maintenance by excising mispaired thymine and uracil in a CpG context and also participates in transcriptional regulation via gene-specific CpG demethyla...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831317/ https://ncbi.nlm.nih.gov/pubmed/19966277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1097 |
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