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Mutational analysis of the 5′-OH oligonucleotide phosphate acceptor site of T4 polynucleotide kinase
T4 polynucleotide kinase/phosphatase (Pnkp) exemplifies a family of bifunctional enzymes with 5′-kinase and 3′-phosphatase activities that function in nucleic acid repair. The N-terminal kinase domain belongs to the P-loop phosphotransferase superfamily. The kinase is distinguished by a tunnel-like...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831316/ https://ncbi.nlm.nih.gov/pubmed/19966275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1096 |
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