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Selection of bacteriophage λ integrases with altered recombination specificity by in vitro compartmentalization
In vitro compartmentalization (IVC) was employed for the first time to select for novel bacteriophage λ integrase variants displaying significantly enhanced recombination activity on a non-cognate target DNA sequence. These variants displayed up to 9-fold increased recombination activity over the pa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831311/ https://ncbi.nlm.nih.gov/pubmed/19966270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1089 |
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