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Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
Helix 38 (H38) of the large ribosomal subunit, with a length of 110 Å, reaches the small subunit through intersubunit bridge B1a. Previous cryo-EM studies revealed that the tip of H38 moves by more than 10 Å from the non-ratcheted to the ratcheted state of the ribosome while mutational studies impli...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831300/ https://ncbi.nlm.nih.gov/pubmed/19952067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1057 |
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