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Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease
BACKGROUND: Late-onset Alzheimer disease (LOAD) is a common disorder with a substantial genetic component. We postulate that many disease susceptibility variants act by altering gene expression levels. METHODS: We measured messenger RNA (mRNA) expression levels of 12 LOAD candidate genes in the cere...
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Academy of Neurology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830916/ https://ncbi.nlm.nih.gov/pubmed/20142614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181d07654 |
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