Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

BACKGROUND: Late-onset Alzheimer disease (LOAD) is a common disorder with a substantial genetic component. We postulate that many disease susceptibility variants act by altering gene expression levels. METHODS: We measured messenger RNA (mRNA) expression levels of 12 LOAD candidate genes in the cere...

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Bibliografische gegevens
Hoofdauteurs: Zou, F., Carrasquillo, M. M., Pankratz, V. S., Belbin, O., Morgan, K., Allen, M., Wilcox, S. L., Ma, L., Walker, L. P., Kouri, N., Burgess, J. D., Younkin, L. H., Younkin, Samuel G., Younkin, C. S., Bisceglio, G. D., Crook, J. E., Dickson, D. W., Petersen, R. C., Graff-Radford, N., Younkin, Steven G., Ertekin-Taner, N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Academy of Neurology 2010
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830916/
https://ncbi.nlm.nih.gov/pubmed/20142614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181d07654
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