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Vascular Endothelial Growth Factor Overexpression Delays Neurodegeneration and Prolongs Survival in Amyotrophic Lateral Sclerosis Mice

We sought genetic evidence for the involvement of neuronal vascular endothelial growth factor (VEGF) in amyotrophic lateral sclerosis (ALS). Mice expressing human ALS mutant superoxide dismutase-1 (SOD1) were crossed with mice that overexpress VEGF in neurons (VEGF(+/+)). We report that SOD1(G93A)/V...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wang, Yaoming, Ou Mao, Xiao, Xie, Lin, Banwait, Surita, Marti, Hugo H., Greenberg, David A., Jin, Kunlin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830908/
https://ncbi.nlm.nih.gov/pubmed/17215390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4433-06.2007
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