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VITAMIN D-DEPENDENT SUPPRESSION OF ENDOTHELIN-INDUCED VASCULAR SMOOTH MUSCLE CELL PROLIFERATION THROUGH INHIBITION OF CDK2 ACTIVITY

1,25 dihydroxyvitamin D(3) (1,25 (OH)2 D) and its less hypercalcemic analogues have been shown to inhibit the proliferation of vascular smooth muscle cells (VSMC) in culture. However, the mechanism(s) underlying this suppression is not well understood. Here we have shown that 1,25 (OH)2 D and its an...

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Detalhes bibliográficos
Main Authors: CHEN, SONGCANG, LAW, CHRISTOPHER S., GARDNER, DAVID G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830853/
https://ncbi.nlm.nih.gov/pubmed/19961935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.11.002
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