Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms

Objective. This study was designed to investigate whether leptin modifies angiotensin (Ang) II-induced proliferation of aortic vascular smooth muscle cells (VSMCs) from 10-week-old male Wistar and spontaneously hypertensive rats (SHR), and the possible role of nitric oxide (NO). Methods. NO and NO s...

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Bibliographische Detailangaben
Hauptverfasser: Rodríguez, Amaia, Gómez-Ambrosi, Javier, Catalán, Victoria, Fortuño, Ana, Frühbeck, Gema
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879542/
https://ncbi.nlm.nih.gov/pubmed/20592755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/105489
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