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Siglecs as targets for therapy in immune cell mediated disease

The sialic acid-binding immunoglobulin-like lectins (siglecs) comprise a family of receptors that are differentially expressed on leukocytes and other immune cells. The restricted expression of several siglecs to one or a few cell types makes them attractive targets for cell-directed therapies. The...

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Autori principali: O’Reilly, Mary K., Paulson, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830709/
https://ncbi.nlm.nih.gov/pubmed/19359050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2009.02.005
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