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Tpl2 is a key mediator of arsenite-induced signal transduction

Arsenite is a well-known human carcinogen that especially targets skin. The tumor progression locus 2 (Tpl2) gene encodes a serine/threonine protein kinase that is overexpressed in various cancer cells. However, the relevance of Tpl2 in arsenite-induced carcinogenesis and the underlying mechanisms r...

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Detalhes bibliográficos
Main Authors: Lee, Kyung Mi, Lee, Ki Won, Bode, Ann M., Lee, Hyong Joo, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830613/
https://ncbi.nlm.nih.gov/pubmed/19808956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2316
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