Transforming Growth Factor-β (TGFβ)-mediated Phosphorylation of hnRNP E1 Induces EMT via Transcript Selective Translational Induction of Dab2 and ILEI

TGFβ induces epithelial-mesenchymal transdifferentiation (EMT) accompanied by cellular differentiation and migration. Despite extensive transcriptomic profiling, identification of TGFβ-inducible, EMT-specific genes has met with limited success. Here, we identify a post-transcriptional pathway by whi...

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Hlavní autoři: Chaudhury, Arindam, Hussey, George S., Ray, Partho S, Jin, Ge, Fox, Paul L., Howe, Philip H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830561/
https://ncbi.nlm.nih.gov/pubmed/20154680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2029
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