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Effect of ligands that increase cAMP on caerulein-induced zymogen activation in pancreatic acini

The pathological activation of proteases within the pancreatic acinar cell is critical to initiating pancreatitis. Stimulation of acinar cells with supraphysiological concentrations of the CCK analog caerulein (CER) leads to protease activation and pancreatitis. Agents that sensitize the acinar cell...

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Autors principals: Lu, Z., Kolodecik, T. R., Karne, S., Nyce, M., Gorelick, F.
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830556/
https://ncbi.nlm.nih.gov/pubmed/12881228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00213.2003
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