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Short and long-term changes in gene expression mediated by the activation of TLR9

CpG DNA binds to Toll-like receptor 9 to stimulate a strong innate immune response. The magnitude, duration and scope of CpG-induced changes in gene expression is incompletely understood despite extensive studies of TLR9 mediated signal transduction pathways. In particular, the prolonged effects of...

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Detalhes bibliográficos
Main Authors: Klaschik, Sven, Tross, Debra, Shirota, Hidekazu, Klinman, Dennis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830361/
https://ncbi.nlm.nih.gov/pubmed/20005572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.11.014
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