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Synthetic oligonucleotides as modulators of inflammation
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs mimic the immunostimulatory activity of bacterial DNA. CpG ODN directly stimulate human B cells and plasmacytoid dendritic cells, promote the production of Th1 and proinflammatory cytokines, and trigger the maturation/activatio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Society for Leukocyte Biology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538593/ https://ncbi.nlm.nih.gov/pubmed/18430787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1107775 |
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