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Expression, purification and primary crystallographic study of human androgen receptor in complex with DNA and coactivator motifs
The androgen receptor (AR) is a DNA-binding and hormone-activated transcription factor that plays critical roles in the development and progression of prostate cancer. The transcriptional function of AR is modulated by intermolecular interactions with DNA elements and coactivator proteins, as well a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830347/ https://ncbi.nlm.nih.gov/pubmed/19995608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2009.12.002 |
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