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Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure

Arsenite is an environmental pollutant. Exposure to inorganic arsenic in drinking water is associated with elevated cancer risk, especially in skin. Arsenite alone does not cause skin cancer in animals, but arsenite can enhance the carcinogenicity of solar UV. Arsenite is not a significant mutagen a...

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מידע ביבליוגרפי
Main Authors: Komissarova, Elena V., Rossman, Toby G.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830301/
https://ncbi.nlm.nih.gov/pubmed/20036271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.12.014
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