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Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure

Arsenite is an environmental pollutant. Exposure to inorganic arsenic in drinking water is associated with elevated cancer risk, especially in skin. Arsenite alone does not cause skin cancer in animals, but arsenite can enhance the carcinogenicity of solar UV. Arsenite is not a significant mutagen a...

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Detalhes bibliográficos
Main Authors: Komissarova, Elena V., Rossman, Toby G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830301/
https://ncbi.nlm.nih.gov/pubmed/20036271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.12.014
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