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Transcription-dependent silencing of inducible convergent transgenes in transgenic mice

BACKGROUND: Silencing of transgenes in mice is a common phenomenon typically associated with short multi-copy transgenes. We have investigated the regulation of the highly inducible human granulocyte-macrophage colony-stimulating-factor gene (Csf2) in transgenic mice. RESULTS: In the absence of any...

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Détails bibliographiques
Auteurs principaux: Calero-Nieto, Fernando J, Bert, Andrew G, Cockerill, Peter N
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830199/
https://ncbi.nlm.nih.gov/pubmed/20180972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-3
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