A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Cell-type-specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of 4 knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTomato and ChR2-EYFP, halorhodopsin eNpHR3.0, a...

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Detalhes bibliográficos
Main Authors: Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A., Garcia, Alfredo J., Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M., Boyden, Edward S., Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R., Svoboda, Karel, Han, Xue, Turner, Eric E., Zeng, Hongkui
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337962/
https://ncbi.nlm.nih.gov/pubmed/22446880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3078
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