A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Cell-type-specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of 4 knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTomato and ChR2-EYFP, halorhodopsin eNpHR3.0, a...

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Main Authors: Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A., Garcia, Alfredo J., Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M., Boyden, Edward S., Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R., Svoboda, Karel, Han, Xue, Turner, Eric E., Zeng, Hongkui
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337962/
https://ncbi.nlm.nih.gov/pubmed/22446880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3078
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