A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Cell-type-specific expression of optogenetic molecules allows temporally precise manipulation of targeted neuronal activity. Here we present a toolbox of 4 knock-in mouse lines engineered for strong, Cre-dependent expression of channelrhodopsins ChR2-tdTomato and ChR2-EYFP, halorhodopsin eNpHR3.0, a...

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Bibliografiske detaljer
Main Authors: Madisen, Linda, Mao, Tianyi, Koch, Henner, Zhuo, Jia-min, Berenyi, Antal, Fujisawa, Shigeyoshi, Hsu, Yun-Wei A., Garcia, Alfredo J., Gu, Xuan, Zanella, Sebastien, Kidney, Jolene, Gu, Hong, Mao, Yimei, Hooks, Bryan M., Boyden, Edward S., Buzsáki, György, Ramirez, Jan Marino, Jones, Allan R., Svoboda, Karel, Han, Xue, Turner, Eric E., Zeng, Hongkui
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337962/
https://ncbi.nlm.nih.gov/pubmed/22446880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3078
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