Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A(2B) adenosine receptor signaling

Priapism is a condition of persistent penile erection in the absence of sexual excitation. Of men with sickle cell disease (SCD), 40% display priapism. The disorder is a dangerous and urgent condition, given its association with penile fibrosis and eventual erectile dysfunction. Current strategies t...

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Autori principali: Wen, Jiaming, Jiang, Xianzhen, Dai, Yingbo, Zhang, Yujin, Tang, Yuxin, Sun, Hong, Mi, Tiejuan, Phatarpekar, Prasad V., Kellems, Rodney E., Blackburn, Michael R., Xia, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Federation of American Societies for Experimental Biology 2010
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830141/
https://ncbi.nlm.nih.gov/pubmed/19858092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-144147
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