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Excess adenosine in murine penile erectile tissues contributes to priapism via A(2B) adenosine receptor signaling

Priapism, abnormally prolonged penile erection in the absence of sexual excitation, is associated with ischemia-mediated erectile tissue damage and subsequent erectile dysfunction. It is common among males with sickle cell disease (SCD), and SCD transgenic mice are an accepted model of the disorder....

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Main Authors: Mi, Tiejuan, Abbasi, Shahrzad, Zhang, Hong, Uray, Karen, Chunn, Janci L., Xia, Ling Wei, Molina, Jose G., Weisbrodt, Norman W., Kellems, Rodney E., Blackburn, Michael R., Xia, Yang
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267015/
https://ncbi.nlm.nih.gov/pubmed/18340377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33467
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