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PYK2 interacts with MyD88 and regulates MyD88-mediated NF-κB activation in macrophages

PYK2, a major cell adhesion-activated tyrosine kinase, is highly expressed in macrophages and implicated in macrophage activation and inflammatory response. However, mechanisms by which PYK2 regulates inflammatory response are beginning to be understood. In this study, we demonstrate that PYK2 inter...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xi, Cai-Xia, Xiong, Fei, Zhou, Zheng, Mei, Lin, Xiong, Wen-Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830122/
https://ncbi.nlm.nih.gov/pubmed/19955209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0309125
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