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Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK–MAPK pathway
Nickel (Ni) is a known carcinogen, although the mechanism of its carcinogenicity is not clear. Here, we provide evidence that Ni can induce phosphorylation of histone H3 at its serine 10 residue in a c-jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK)-dependent manner. Ni induces th...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829883/ https://ncbi.nlm.nih.gov/pubmed/18375956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn084 |
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