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Lipotoxicity Mediated Cell Dysfunction and Death Involves Lysosomal Membrane Permeabilization and Cathepsin L Activity

Lipotoxicity, which is triggered when cells are exposed to elevated levels of free fatty acids, involves cell dysfunction and apoptosis and is emerging as an underlying factor contributing to various pathological conditions including disorders of the central nervous system and diabetes. We have show...

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Bibliografiska uppgifter
Huvudupphovsmän: Almaguel, Frankis G., Liu, Jo-Wen, Pacheco, Fabio J., De Leon, Daisy, Casiano, Carlos A., De Leon, Marino
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829674/
https://ncbi.nlm.nih.gov/pubmed/20043885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.12.038
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