Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apoptosis in CRC cells and may therefore be relevant in CRC prevention and therapy. We previously reported...

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Autores principales: Marques, C, Oliveira, C S F, Alves, S, Chaves, S R, Coutinho, O P, Côrte-Real, M, Preto, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734821/
https://ncbi.nlm.nih.gov/pubmed/23429293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.29
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