Vascular smooth muscle cell-selective PPARγ deletion leads to hypotension

BACKGROUND: Peroxisome proliferator-activated receptor-γ (PPARγ) agonists are commonly used for the treatment of diabetes although their PPARγ-dependent effects transcend their role as insulin sensitizers. Thiazolidinediones lower blood pressure (BP) in diabetic patients while results from conventio...

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Hlavní autoři: Chang, Lin, Villacorta, Luis, Zhang, Jifeng, Garcia-Barrio, Minerva T., Yang, Kun, Hamblin, Milton, Whitesall, Steven E., D'Alecy, Louis G., Chen, Y. Eugene
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829656/
https://ncbi.nlm.nih.gov/pubmed/19364979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.815803
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